Even though hypersensitive call dermatitis can be classified a "allergic" reaction (which usually identifies sort I hypersensitivity), the pathophysiology really requires a reaction which more correctly fits with a sort IV hypersensitivity reaction. [51] Throughout sort IV hypersensitivity, there may be initial of selected varieties of Capital t cellular material (CD8+) which destroy targeted cellular material upon call, in addition to stimulated macrophages which develop hydrolytic enzymes.
